Correlation Between Salivary Amylase A Biomarker And Postoperative Pain After Third Molar Surgery

Abstract

Objective – This paper investigates and analyses the relationship of postoperative pain with that of salivary alpha amylase a salivary
biomarker after third molar surgery.
Study design – A prospective study was performed using 10 patients who had undergone surgical extraction of impacted mandibular
third molars. All extractions were performed under local anesthesia. Swelling, maximum inter-incisal distance and mean visual pain
analogue scale were determined accordingly.
Results – A total of 20 extractions was performed. 2 samples of saliva were taken from each patient that is before extraction and
immediately after extraction. The average value of the marker was compared in the study. Statistical analysis revealed that salivary
alpha amylase was not related to the inflammatory response after third molar surgery.
Conclusion - this study indicate salivary amylase is not a reliable marker and the need for further research on this to identify those
factors that are linked to inflammation after lower third molar extraction and to the betterment of how they are affected during the
postoperative period