The influence of PH on skin’s surface

Authors

  • Ayushi Sehgal
  • Anju Singh

DOI:

https://doi.org/10.47750/pnr.2022.13.S01.236

Keywords:

corneocyte, epidermal differentiation, lipid production, stratum corneum’s homeostasis, wounds.

Abstract

The pH of skin is very decisive in the life of humans because it helps in enhancing infections that are related to antimicrobials. So far, the skin of humans considered is the main outdoor for several bacterial infections. The acidic Nature (pH) of the skin performs an integral physiologically part in the body and it has been identified as a regulatory component in the stratum corneum’s homeostasis and skin barrier permeability. Surveys were done later illustrated that aggregation, skin barrier function& lipid production, epidermal differentiation& desquamation are basically impacted by the pH itself. Multiple epidermal pH figures have also been observed and tested in this study, all within the acidic condition however varying from pH 4.0 to 7.0, and depending on this pH, the 'natural' skin surface pH is expected to be 4.7 to 5.75 or 6. In addition, various studies are available in the latest days that focused primarily on alterations inside the pH of the stratum corneum's deeper layers including the effect of various physiological and pathological variables. Whenever the skin barrier is compromised, pH rises, resulting in a variety of ailments, including dermatitis, irritating contact dermatitis, ichthyosis, acne, and dry and ageing skin. In the current review, we will summarise many autogenous factors and exogenic factors such as skin moisture, sweat, sebum (produced by sebaceous glands), anatomic site, genetic susceptibility, age, detergents, so-called skin health maintenance products, wounds occlusive dressing could bother the pH of the skin. With that, we collected several publications in this review and explored the importance of pH surface and the key factors that influence skin’s pH-related skin illness. We'll also go over how to determine the pH of the surface of the skin and also how it would affect skin and wounds.

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Published

2022-10-05

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Section

Articles

How to Cite

The influence of PH on skin’s surface. (2022). Journal of Pharmaceutical Negative Results, 2012-2023. https://doi.org/10.47750/pnr.2022.13.S01.236