Correlation Of Monocyte Chemoattractant Protein-1 With Female Unexplained Infertility

Abstract

Objective: to contrast the serum MCP-1 concentration between women who have main or secondary unexplained infertility and fertile
women (control group). Methods: Case-control research was done using data from November 2021 to March 2022. The study population consisted of 102 females with primary and secondary unexplained infertility and 82 apparently healthy reproductive women (who have at least one child) but are not pregnant. monocyte chemoattractant protein 1 was evaluated using a customized commercial kit developed by the Bioassay Technology Laboratory and quantified by Sandwich Enzyme-Linked Immunosorbent Assay. Results: In this investigation, we discovered that the case group's mean serum MCP-1 concentration was considerably lesser (265.59 156.9 ng/L) than the control group's (358.11 286.1 ng/L), with a p-value of less than (0.05) and, There were no statistically significant variations in the MCP-1 concentration. in relation to primary or secondary infertility and to the duration of the disease in the study groups, Conclusion: we found there is no significance association between the type of infertility on the serum concentration of the MCP-1.