Natural Superdisintegrant: A Key Ingredient for Orodispersible Dosage Form

Abstract

Background: Orally disintegrating tablets have been shown to have better patient compliance and drug solubility than conventional tablets in numerous studies that examined them in vitro and in vivo. However, there are several requirements for the preparation of tablets as orodispersible forms using the pharmaceutical active components. This dosage type can be prepared in a variety of methods, and each manner has advantages and disadvantages. Because of their increased compliance, bioavailability, simplicity of administration, and superior palatability, orodispersible

Objective: Tablets are pharmacological formulations that are used to achieve rapid therapeutic effect. These medications are typically advised for elderly and paediatric patients due to its various benefits, this dosage form is an effective means to deliver the active medication ingredients.

Method: The inclusion criteria for the qualitative literature review are met by Pub Med, Scopus, Web of Science, Google Scholar, Google Books, and Science Direct.

Conclusion: In this review, many types of orodispersible tablets are commercially accessible. Some active medicinal components must be taste masked before into orally disintegrating tablets. Due to this, a certain patient population—including dyslexic, bedridden, psychic, elderly, and paediatric patients—has been drawn to the market by different dose forms. Numerous techniques have recently been developed to improve the fragile dosage forms' capacity to dissolve without losing their integrity.