Diagnostic Utility Of Scrape Cytology In The Intraoperative Diagnosis Of Breast Lumps

Abstract

INTRODUCTION: Scrape cytology is a modification of imprint cytology in the rapid  intraoperative  diagnosis of tumors. There are many controversies in rapid diagnosis of surgically removed specimens and single completely reliable method has not yet been developed. The study is undertaken to evaluate the role of scrape cytology  which does not require special setup in the diagnosis of intraoperative lesions of breast.

OBJECTIVES : To perform scrape cytology of  surgically operable  breast masses and evaluate its accuracy in relation to histopathological diagnosis.

MATERIALS AND METHODS : A total of 82 surgically resected specimens  from breast were examined by scrape cytology before formalin fixation  and compared with histopathological sections which were considered as gold standard.

RESULTS : Total  82 cases were subjected to scrape cytology  78 cases was given cytological  diagnosis  . Among 78  cases 43  were benign  35 were malignant lesions in comparison with histopathology showing  sensitivity,specificity and accuracy of 100%,82.86% and 92.31%  respectively .

Conclusion : Intraoperative scrape cytology is a  good complement to histopathology in the diagnosis of cancer where frozen section facilities are  often not available, since a rapid preliminary diagnosis may help in surgical management planning  .