Is statistical significance a relevant tool for assessing clinical significance?
Abstract
In medicine and psychology, clinical significance refers
to either of two related but slightly dissimilar concepts,
whereby certain findings or differences, even if measurable
or statistically confirmed, either may or may not have
additional significance, either by[1] being of a magnitude
that conveys practical relevance (a usage that conflates
practical and clinical significance interchangeably) or[2]
more technically and restrictively addresses whether an
intervention or treatment may or may not fully correct
the finding. Commentators who utilize the second,
more restrictive usage designate the broader usage as
linguistically imprecise and thus erroneous. Now a days,
there is an element of statistics in the clinical assessment
of therapeutic or outcome analysis.