Lack of antiglycation activity of fresh juice of whole plant of Enicostema axillare (Lam.) Raynal

Abstract

Objective: To investigate the antiglycation potential of fresh juice of whole plant of
Enicostema axillare (Lam.) Raynal. in vitro. Materials and Methods: Antiglycation
activity of fresh juice of whole plant was determined in vitro using five concentrations
(25, 50, 100, 200, and 400 μg/ml) by determining their ability to inhibit the formation
of advanced glycation endproducts in a bovine serum albumin / glucose system using
fluorescence spectroscopy. Results: There is no antiglycation activity in vitro of fresh juice
of E. axillare plant. Conclusion: It is unlikely that impairment of diabetic complications
by E. axillare whole plant juice as claimed by ayurvedic and traditional physicians is
mediated via antiglycation activity