Twenty-five Years of Laser Therapy: Causes and Treatment Results in the Pulmonology Ward of Imam Reza Hospital, Tabriz - Iran

Authors

  • Mohammad-Esmaeil Hejazi

Keywords:

Benign, Laser therapy, Malignant, Recanalization, Tracheal stenosis

Abstract

ntroduction: Causes of laser therapy include airway obstruction with atelectasis, abscesses, distal pneumonia, uncontrollable
cough, dyspnea or hemoptysis, especially, when a patient refuses other therapeutic methods or other methods are not effective
immediately.
Methods: Data regarding patients who had undergone laser therapy with bronchoscopy in the past 25 years, in pulmonology
ward of Imam Reza Hospital, Tabriz, Iran, were gathered. Causes of laser therapy and the results of the treatment along with
complications were recorded. Holmium, Nd:YAG or APC was implemented.
Results: There were 281 patients (63.8%) with benign lesions, while patients with malignant lesions included 159 cases (36.2%).
Tracheal stenosis was the most frequent benign lesion (233 cases, 53%), whereas squamous cell carcinoma (SCC) was the most
frequent amongst malignant ones (66 cases, 15%). Altogether, patients underwent laser therapy for 1190 times. The mean of
treatment sessions for each patient was 2.90±2.04 times. Recanalization, as an outcome of the treatment, was higher in benign
cases (P<0.001). In 221 patients (78.82%) with benign lesions, 50% recanalization was achieved, while in malignant cases, only
in 39 patients (24.13%) 50% recanalization happened.
Conclusion: Patients were mostly treated for benign lesions, with tracheal stenosis being the most frequent case. Laser therapy
was shown to be a safe method for treating airway obstruction, with very low complications, independent from the type of
the lesion. However, it was more efficient in treating benign lesions than malignant ones. Type of the lesion (i.e., benign or
malignant) was the main factor for treatment response, in this study.

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Published

2022-01-30

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Articles

How to Cite

Twenty-five Years of Laser Therapy: Causes and Treatment Results in the Pulmonology Ward of Imam Reza Hospital, Tabriz - Iran. (2022). Journal of Pharmaceutical Negative Results, 13(1), 44-49. https://pnrjournal.com/index.php/home/article/view/186