Homeostasis of Pigs at Different Schemes of Use of “Protamin” Feed Additive


  • Krapivina E.V


Feed additive; Morphological and biochemical blood parameters; live weight. Pigs.


The conduct of industrial pig breeding involves technological stresses that cause adaptive changes in the body, requiring additional energy
consumption, which negatively affects the productivity of animals. By influencing the formation of the body’s adaptive reactions with
biologically active substances, it is possible to reorient metabolic processes towards anabolism. It is known that the use of biologically
active substances optimizes homeostasis, but the modes of their use require clarification. In order to study the influence of the scheme of
feeding the feed additive “Yeast hydrolysate “Protamin” on the homeostasis of pigs in different periods after the introduction of antigens and
against the background of pre-slaughter manipulations were formed 3 groups of piglets of 10 heads of 58-61 days of age with a live weight
of 11.16 ± 0.01kg. Animals of group 1 were control, piglets of group 2 received 5 grams of feed supplement “Yeast hydrolyzate” Protamin”
with water once a day (individually using a feed injector) for 2 months according to the following scheme: 7 days - drinking, 7 days - a
break; animals of group 3 received the same amount of supplements, but according to the scheme: 7 days - drinking, 14 days - a break. The
hemogram indices of the experimental animals were determined using the “Abacus junior vet 5” hemanalyzer. Biochemical parameters of
blood serum were determined at the testing center of the Federal State Budgetary Educational Institution “Bryansk Interregional Veterinary
Laboratory” according to generally accepted methods. The animals were weighed individually. It was found that the feeding of the feed
additive “Protamin” to pigs for 2 months according to both schemes led to a high level of anabolism in a month after the end of drinking the
drug, more pronounced in pigs receiving the drug according to the scheme: 7 days - drinking, 7 days - a break. They have a higher level of
energy metabolism. The use of this scheme of feeding the additive promoted the formation of a calm activation reaction in animals in the
absence of stress factors and the optimization of homeostasis, and under conditions of pre-slaughter manipulations - a reaction of increased
activation, caused an increase in the level of reactivity of the organism in pigs and provided a significant increase in live weight by 13.57 and
22.70% respectively. Output. For the formation of adaptive reactions in pigs, ensuring the optimization of homeostasis and an increase in
live weight, the most effective scheme for the feeding of the feed additive “Yeast hydrolysate “Protamin”: 7 days - drinking, 7 days - a break.







How to Cite

Homeostasis of Pigs at Different Schemes of Use of “Protamin” Feed Additive. (2021). Journal of Pharmaceutical Negative Results, 12(2), 6-17. https://pnrjournal.com/index.php/home/article/view/174