Larvicidal Activity of Chemically Synthesized Silver Nanoparticles Against Anopheles stephensi


  • Mahmoud Osanloo


Chemical reduction, larvicidal activity and Anopheles stephensi, silver nanoparticles, silver nitrate, sodium borohydride


Background: Silver nanoparticles (AgNPs) have wide applications in different fields such as medicine, food industry, and pest management.
Larvicidal activity of many herbally biosynthesized AgNPs have been evaluated against main malaria vector, that is, Anopheles stephensi.
However, results of the studies are very different. No report has been found on larvicidal activity of chemically synthesized AgNPs against
A. stephensi. Materials and Methods: AgNPs were synthesized using chemical reduction and characterized by dynamic light scattering and
transmission electron microscopy. Concentration of silver ion in the final solution was determined by ICP‑AES. Turbidity of solutions of
AgNPs at different concentrations(i.e., 0.2–100 ppm) was studied. Subsequently, larvicidal activity of nanoparticles was evaluated, in line with
the WHO guideline for laboratory tests. Results: AgNPs were synthesized successfully and confirmed by ultraviolet analysis. Nanoparticles
were spherical with a diameter of ~30 nm. AgNPs had no larvicidal activity up to 80 ppm and showed a small larvicidal effect (~20%) at
100 ppm. Conclusion: Chemically synthesized AgNPs are not proper candidates for control of larvae due to their low efficacy and effects on
nontarget specious lived in stagnant water.







How to Cite

Larvicidal Activity of Chemically Synthesized Silver Nanoparticles Against Anopheles stephensi. (2019). Journal of Pharmaceutical Negative Results, 10(1), 69-72.