The Effectiveness of Melissa officinalis on Sleep Problem in Patients with Chronic Heart Failure
Keywords:
Heart failure, Melissa officinalis, sleepAbstract
Background: Numerous studies have documented high prevalence rate of major depression in patients with heart failure. The aim of
the present study was to evaluate the effectiveness of Melissa officinalis on sleep problem in patients with chronic heart failure (CHF).
Materials and Methods: In a randomized, controlled trial study, eighty patients (40 in each group) with CHF experiencing insomnia were
allocated randomly into intervention and control groups. The patients in intervention group received 12 ml M. officinalis syrup in addition to
conventional treatment 1 h before going to bed for 4 weeks. A demographic questionnaire and the Pittsburgh Sleep Quality Index were used
to collect data. Questionnaires were completed by all individuals before and after the intervention. Results: The time duration of waiting for
falling into sleep in intervention group was significantly less than control group (P = 0.001). The hours during which the individuals were
fully asleep were significantly more than control group (P < 0.05). Conclusion: M. officinalis may improve the quality of sleep in patients
with CHF who experience insomnia.
