Effect Of Body Mass Index On The Biochemical Outcome After Fresh Embryo Transfer In Women With And Without Polycystic Ovary Syndrome (PCOS)

Authors

  • Surleen Kaur, Irsad Ahamad, M. Gouri Devi, Rita Singh

DOI:

https://doi.org/10.47750/pnr.2021.12.01.12

Abstract

Aim: To evaluate the influence of body mass index (BMI) on the biochemical outcome of fresh embryo transfer in women with and without polycystic ovary syndrome (PCOS).

Methodology: A retrospective study on biochemical outcome after fresh embryo transfer was done for a total of 230 patients with a diagnosis of PCOS and 556 non-PCOS women who were undergoing IVF due to male infertility or tubal factor. PCOS as well as non-PCOS women were categorised based on their BMI. Total oocytes retrieved, average oocytes, mature oocytes, average mature oocytes, mature oocyte rate, fertilization Rate, total ETs  and positive biochemical outcome were compared among BMI categories.

Result:

Among the 230 patients with a diagnosis of PCOS, 62 had BMI ≤ 24 and 168 had BMI ≥ 25. Among the 556 non-PCOS women, 220 had BMI ≤ 24 and 336 had BMI ≥ 25. The age of women with PCOS and without PCOS in all the groups was not significantly different. The average number of oocyte retrieved and matured were higher in PCOS group, however, the rate of fertilization was lower in PCOS group than in non-PCOS group and was independent of BMI. The percentage of negative biochemical outcome was comparable between the PCOS and non-PCOS group with BMI≤ 24. However, percentage of the positive biochemical outcome was significant less in PCOS women than the non-PCOS women with BMI ≥ 25 (25.57% vs. 42.25%).

Conclusion: The present study show an increase in percentage of negative biochemical outcome in women with PCOS with BMI ≥ 25 after fresh embryo transfer than in the non-PCOS group. However, the rate of oocyte maturation was not significantly different.

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Published

— Updated on 2021-12-31

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How to Cite

Effect Of Body Mass Index On The Biochemical Outcome After Fresh Embryo Transfer In Women With And Without Polycystic Ovary Syndrome (PCOS). (2021). Journal of Pharmaceutical Negative Results, 12(1), 74-79. https://doi.org/10.47750/pnr.2021.12.01.12