Exploring the Potential of Nanoparticle-Mediated Therapy for Cardiovascular Disease: A Systematic Review

Abstract

Cardiovascular disease (CVD) is a rapidly growing problem due to sedentary lifestyles and is associated with high morbidity and mortality. Despite available diagnostic and treatment options, these are not fully effective, calling for alternative approaches. Nanomedicine presents a promising solution by exploring the potential of nanoparticles (NP) for CVD diagnosis and therapeutic applications. As a controlled drug delivery system, NPs have demonstrated the ability to provide targeted drug delivery due to their unique multi-functionality. A comprehensive review of the current state of CVD diagnosis and treatment was conducted using electronic databases, including Science Direct, PubMed, Scopus, Web of Science, ProQuest, and Willey Online Library. This review summarizes the current limitations of CVD diagnosis and treatment and highlights the potential of NP application in both diagnosis and treatment, while also discussing its potential toxicity.