The Effect of Nano-Cinnamomum Capsule on Blood Glucose, And Lipid Profile in Type 2 Diabetic Male Rats

Authors

  • Zahida Miran Hussein

DOI:

https://doi.org/10.47750/pnr.2022.13.03.107

Keywords:

antioxidant enzymes; Nano-Cinnamomum; Fragaria; cholesterol; HbA1c.

Abstract

Objective: High blood sugar caused by problems with insulin secretion, action, or both, or insulin resistance characterizes diabetes mellitus. Cinnamon inhibits NF-B signaling. This study examines Nano-effects Cinnamomum's on diabetic rats' HbA1C, fasting blood sugar, and lipid profile.
Materials and Methods: The experiment fed rats HFD for 4 weeks. After that, they were injected with 35 mg/kg STZ to cause T2DM. After 4 weeks of Se-NPs and MET, synergistic effects on diabetic complications were examined. We ran molecular and biochemical tests on insulin sensitivity, oxidative mediators, and inflammatory markers.
Results: Mean age, BMI, FBG, total cholesterol, triglycerides, LDL, HDL, HbA1c, and sex were the same at the start. Comparing results before and after treatment (p 0.05), the Nano-Cinnamomum group had lower HbA1C, FBG, TG, and BMI.
When values before and after treatment were compared, it was clear that HbA1c, eAG, LDL-C, and BMI had changed (p0.05).
Conclusion: These results show that Nano-Cinnamomum may lower HbA1c in people with type 2 diabetes. It may also partially lower serum LDL-C and BMI.

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Published

2022-09-17

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Section

Articles

How to Cite

The Effect of Nano-Cinnamomum Capsule on Blood Glucose, And Lipid Profile in Type 2 Diabetic Male Rats. (2022). Journal of Pharmaceutical Negative Results, 13(3), 709-714. https://doi.org/10.47750/pnr.2022.13.03.107