“Formulation And Evaluation Of Nutraceutical Tablet Of Polyherbal Drugs By Wet Granulation”

Abstract

Introduction: The current study's goal was to Develop and Test Nutraceutical Tablets containing various herbal drug combinations.

Material and Method : The Nutraceuticals tablet contains Magnesium Stearate and Aerosol as lubricants, HPMC as a binder, and natural drugs such as Guduchi, Amla, Aloe Vera, and Brahmi that were prepared using the Wet Granulation Method. Several Evaluation parameters, including Appearance, Thickness, Weight Variation, Hardness and Friability, and HPTLC Analysis, were applied to the compressed formulations. All of the Nutraceutical tablet evaluation parameters yielded acceptable results. Pre-compression studies on nutraceutical tablets yield positive results. Nutraceutical tablet thickness, hardness, weight variation, and friability were found to be within acceptable limits. The current study yielded significant results of the HPTLC study yielded a satisfactory acceptable result. Based on the findings, HPTLC Fingerprint analysis carries out with a methanol extract of all the herbs with solvent system Chloroform : Methanol : EthylAcetate : Glacial Acetic Acid ( 6:2:2:0:2) usingCAMAG HPTLC system.

Result : From the HPTLC study it is found that the extract and tablet sample is showing good peak and photo capture  at the 254nm ,366nm.. the individual drug & tablet formulation were study for the quantitative estimation it was concluded that the tablet contains an adequate amount of herbal drug.It was clearly found in the current investigation that nutraceuticals might be used to support bodily health. These and other nutricosmetics rich in nutrients and antioxidants may be used to treat and prevent a wide range of illnesses that can benefit from vitamin and antioxidant content. There are well establishment done in the improvement and role of basic nutrient which maintains quality of life , wellness although nutraceuticals have significant role in promoting human health , stronger immune system , prevention of the human disorder., nutrition specialist  have to work strategically to provide ultimate health benefits .

Conclusions : Herbal’s have an different kind of scope in medicinal benefits from immemorial period there is extensive use of the varioius herb is done for the immunity and prevention of the diseases.