Prescription Pattern analysis and utilization of antiepileptic drugs in a tertiary care hospital in Kanchipuram

Authors

  • Nithya Panneerselvam Department of Pharmacology, Sree Balaji Medical College and Hospital, BIHER, Chennai, Tamilnadu, India and Ph.D Scholar, Meen akshi Academy of Higher Education and Research,Chennai.
  • Sai Mani Samhitha Molakala Department of Pharmacology, Meenakshi Medical College hospital and Research Institute, Meenakshi Academy of Higher Education and Research, Kanchipuram, Tamilnadu, India
  • Parimala Kathirvelu Department of Pharmacology, Meenakshi Medical College hospital and Research Institute, Meenakshi Academy of Higher Education and Research, Kanchipuram, Tamilnadu, India
  • Viswanathan Subramanian 5Department of Pharmacology, Meenakshi Medical College hospital and Research Institute, Meenakshi Academy of Higher Education and Research, Kanchipuram, Tamilnadu, India
  • Yogeswari subramanian Department of Pharmacology, Meenakshi Medical College hospital and Research Institute, Meenakshi Academy of Higher Education and Research, Kanchipuram, Tamilnadu, India

DOI:

https://doi.org/10.47750/pnr.2022.13.03.075

Keywords:

newer antiepileptic agents, prescription, epilepsy, utilisation

Abstract

Background: People suffering from epilepsy requires a long period of treatment and regular monitoring. Extensive use of antiepileptic
drugs warrants critical monitoring to suggest appropriate clinical use and safety considerations.

Objectives: The study was aimed to analyse the prescription pattern of antiepileptic drugs in a tertiary care hospital in Kanchipuram. Methodology: This was a prospective, observational study conducted in outpatient departments at Meenakshi medical college Hospital and Research institute. Institutionalethical clearance was obtained.

Results: Monotherapy were prescribed among 69.9% of patients and 30.08% of patients received polytherapy. levetiracetam (23.8%) was the most prescribed drug followed by benzodiazepines (16.8%), hydantoin drugs such as phenytoin, fosphenytoin (11.5%), valproic acid(10.6%) and iminostilbenes such as carbamazepine and oxcarbazepine(5.3%).AEDs were more prescribed only for seizure disorder (79%) than any other disease conditions.

Conclusion: A shift from the use of conventional antiepileptic drugs to the newer AED’s was observed, which dominated the pharmacotherapy of epileptic seizures. This would form a part of pharmacoepidemiology and will update the treatment guidelines benefitting the physicians regarding optimal use of antiepileptic drugs

Downloads

Published

2022-09-21

Issue

Section

Articles

How to Cite

Prescription Pattern analysis and utilization of antiepileptic drugs in a tertiary care hospital in Kanchipuram . (2022). Journal of Pharmaceutical Negative Results, 13(3), 491-496. https://doi.org/10.47750/pnr.2022.13.03.075