The Effectiveness Concentration of Basil Leaf Extract Inhibiting the Growth of Candida Albicans: Literature Review

Abstract

Introduction. Basil (Ocimum Sanctum L.) has long been known and has been used for generations as traditional medicine. Basil has active compounds such as essential oils, alkaloids, saponins, and flavonoids that can inhibit and kill Candida albicans. Candida albicans becomes a pathogen that overgrows on the mucosal surface which then invades the host tissue and spreads into the bloodstream. This fungal infection can cause oral candidiasis or thrush if not treated.

Objective. To determine the effectiveness of the concentration of basil leaf extract which produces a zone of inhibition of the growth of Candida albicans.

Methods. A literature review is a literature research search by reading various books, journals, and other publications related to the topic of writing.

Conclusion. This conclusion shows that basil leaf extract can inhibit the (MIC) growth of Candida albicans at a concentration of 12.5% ​​and can kill (MBC) Candida albicans at a concentration of 25%.