Phytochemicals Screening and evaluation of phoenix dactylifera L. seeds oil functional properties on wound healing in rats

Abstract

The seeds of phoenix dactylifera L. plants have many traditional uses of various kinds for disease, one folklore use of the oil of the plant seeds is the treatment of wound healing. this study undertaken the composition and content of certain bioactive constituents of the oil obtained from phoenix dactylifera L. seeds and the effect of the phoenix dactylifera L. seeds on wound healing in the rats. Uniform wounds were induced on the dorsum of 18 rats, randomly divided into three groups. The wounds were photographed, and topically treated with nothing (control group), 0.13 mg/mm2 of a reference drug (“Mebocream®”), and 0.52 μl/mm2 of phoenix dactylifera oil daily for 12 days and biopsies were histologically assessed. morphometric assessment and histological findings revealed healed biopsies from the plant oil-treated group of rats, unlike untreated group, and a full re-epithelialization with the reappearance of skin appendages and well organized collagen fibers without inflammatory cells.