A study of lipid variations occurring patients in different stages of Chronic Kidney Disease

Abstract

Aim and Background: In this study investigated that the alteration in different lipoprotein fractions in chronic kidney disease patients. Chronic kidney disease is a syndrome, which results from progressive and irreversible destruction of nephrons regardless of the etiology, where the kidney is no longer able to maintain the biochemical homeostasis. The syndrome is complex and the biochemical changes and clinical signs are variable and mostly non-specific. Materials and Methods: This is a cross sectional study. Study conducted on patients attending the departments of General Medicine and biochemistry, Melmaruvathur Adhiparasakthi Institute of Medical Sciences and Research. 100 chronic kidney patients were taken this study. All the patients divided into five groups each group consist of 20 patients. Results: The mean age for the total number of patients was 57.28 yrs. Among 100 CKD patients 77 were on conservative treatment and 23 were on maintenance hemodialysis. Among the 100 CKD patients in the study group stage wise distribution was done. Majority of patients being in stage 5 followed by stage 3. Conclusion: In the present study we conclude that the lipid abnormalities in chronic renal failure accelerates the progression of the renal failure and predisposes to atherosclerosis it is worthwhile detecting and treating hyperlipidemia in chronic renal failure patients.