Comparison Between Subjective And Objective Assessment Of Chemotherapy Induced Peripheral Neuropathy In Cancer Survivor: A Case Study

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) affects 19-85% of individuals who have received neurotoxic chemotherapy.
CIPN is generally assessed subjectively using patient self-report or clinician-reported questionnaires. The goal of this study was to use
mTNS to objectively measure CIPN in patients, as well as to investigate the concordance between mTNS and subjective EORTC QLQ
– CIPN 20 assessment. Patients getting chemotherapy for cancer were recruited at the hospital for this case study. We measured CIPN
using subjective and objective methods, namely the EORTC QLQ – CIPN 20 and the modified total neuropathy score. The prevalence
of patients with abnormal sensation was observed on mTNS and EORTC QLQ – CIPN 20 grading. The level of concordance between
quantitative and subjective measures was poor. CIPN should be evaluated objectively as well as subjectively.