Association between obesity and increase severity of COVID-19

Authors

  • Khalid Hassan Abdalruda
  • Ahmed Hassan Kudhair
  • Bahaa Noor Madhloom

DOI:

https://doi.org/10.47750/pnr.2022.13.03.040

Keywords:

COVID -19, obesity, Inflammatory and coagulation markers.

Abstract

Background: The coronavirus disease 2019 (COVID-19) become pandemic in many countries. Many subsequent data shown that the obesity is a risk factor responsible for severity of COVID-19. Obese COVID-19 patient were significantly associated with elevation the inflammatory markers and coagulated factor. The sex has association with diseases severity specially obese COVID-19 patient, so more likely to become seriously ill ,so those patients will hospitalized and admitted to ICU and more care requirement .
Objective: The ambition of this study is to investigation whether obesity is implicated in exacerbation severity of COVID .19.
Method: 381 COVID -19 patient was participated in this study,185 of them were non obese COVID-19 and the other 196 patient were Obese COVID-19, inflammatory and coagulation marker was measured.
Results: The data show significant higher levels in interleukins IL-6, CRP, TNF-α, Ferritin, and D-dimer and failure to give significant level for IL-10 and glucose concentration among obese , and non-obese, obese based on BMI and depend on the sex .
Conclusion: Obesity is significantly increase the severity of COVID-19 disease. The obese patient displays higher levels for inflammatory and coagulation factor specially in those patients has 35-39.9 BMI compared with normal weight individuals. The data indicated that the sex significantly interact with obesity on to COVID-19 severity enhancing.

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Published

2022-09-20

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Section

Articles

How to Cite

Association between obesity and increase severity of COVID-19. (2022). Journal of Pharmaceutical Negative Results, 13(3), 249-254. https://doi.org/10.47750/pnr.2022.13.03.040