Cardiac Patch Of Myocardial Infraction: A Review

Abstract

One of the most prevalent cardiovascular diseases, myocardial infarction (MI) is a life-threatening condition caused by damage to the myocardium caused by a blockage in one or more of the coronary arteries. Researchers are eager to discover novel strategies for delaying the progression of myocardial injury in order to repair the damaged myocardium in MI. Cardiac patches, which are scaffolds that are layered on top of the heart, have been shown to have a significant curative effect in the treatment of MI. They have the ability to deliver a variety of bioactive cells or factors, enhance cardiac function, and provide mechanical support for the site of an infarction. For use in cardiac patches, biomaterials with certain mechanical and biocompatibility properties have received a lot of attention. This review focuses on recent developments in these biomaterial-based cardiac patches, which can be divided into two categories based on the materials they are made of: (i) natural materials and (ii) synthetic materials. Each type's major benefits and current difficulties are discussed, as is a brief overview of potential research directions.