“A Study On The Impact Of Oral Iron Therapy For Iron Deficiency Anaemia On Serum Lipid Levels In Indian Adults: A Prospective Study”

Abstract

Background: The two most prevalent public health issues are dyslipidaemia and iron deficiency anaemia, notably in developing nations
such as India. There is a correlation between these two serious disorders, however research on Indian people is lacking in this area.
Methods: This is a prospective study to assess the effect of iron treatment on Indian Iron deficiency anaemia (IDA) patients and their
effect on serum lipid profile post iron therapy. In this study, 52 patients with confirmed iron deficiency anaemia with dyslipidaemia were
examined, with a mean age of 49±11 years and a gender distribution of 37 females and 15 men. The serum lipid profile was tested for
changes in (TGL, TC, LDL, HDL, VLDL cholesterol) and After three months of oral iron supplements, the patients were reassessed and
monitored.
Results: The outcomes are reported as mean and standard deviation. Total cholesterol and low-density lipoprotein cholesterol (LDL)
levels were considerably (P < 0.001) higher in the iron deficiency anaemia group (272.2+29.2 mg/dl and 170.1+17.1mg/dl) than in the
post iron therapy group (218.00 28.3 mg/dl and 123.7 + 20.3mg/dl) and the level of very low-density lipoprotein cholesterol (VLDL)
was considerably (P = 0.02) higher in IDA group (61.3+10.7 mg/dl) compared to the post iron therapy group (44+8.9 mg/dl).Similarly,
before therapy IDA and dyslipidaemia group free serum iron was (40.8+8.4) after iron therapy it significantly enhanced to 124.1+14.5.
Conclusion: Present finding concluded that aberrant serum lipid profiles are linked with IDA in Indian adults and iron therapy has a
considerable beneficial effect.