PHYTOCHEMICAL SCREENING AND INVITRO EVALUATION OF WOUND HEALING ACTIVITY, POLYHERBAL PREPARATION USING CHICK EMBRYO MODEL

Abstract

Reportedly, plants such as Cassia angustifolia and Tridax procumbens are used in Siddha medical systems to treat various diseases. Using a chick embryo wound model developed as part of the study, the presented research aimed to determine the wound-healing efficacy of methanol and aqueous extracts of the flowers and leaves. The experimental results show that the methanol extract exhibited good dose-dependent curative efficacy. In the chick embryo chorioallantoic membrane excision wound model, the 300g concentration of polyherbal methanol extract increased wound concentration by 50% compared to the negative control model. Compared to single plants and control groups, the results of the polyherbal Preparation were positive. The extract was also a reliable alternative to animal models for the preliminary screening compounds with wound-healing potential.