Discontinuation Of Levothyroxine In Primary Hypothyroidism And Intracranial Hypertension – Case Series :

Abstract

Idiopathic intracranial hypertension (IIH) is persistent increase in intracranial pressure without any intracranial lesions .IIH is associated
with many conditions eg.SLE, hypothyroidism ,hyperthyroidism , hypoparathyroidism etc. Eleven cases of IIH secondary to
levothyroxine initiation have been reported so far .We report a case series of 3 patients who were known cases of primary
hypothyroidism and were on high dose ( > 100 microgram) levothyroxine therapy ,they discontinued the drug for few weeks and after
reinitiation of levothyroxine developed signs and symptoms of IIH , no other causes for intracranial hypertension were found and they
were treated successfully