To Determine The Anti-Inflammatory And AntiPyretic Activity On The Stem Of Carissa Carandas Linn

Abstract

Plants hold an extraordinary put in the world since they are the establishment forever. In all food frameworks, they are the essential
makers. Plants and spices have been used as a crucial part of medication since long before recorded history. Inflammation is a
pathologic condition that includes a wide range of diseases such as rheumatic and immune-mediated conditions, diabetes,
cardiovascular accident, and etcetera. Anti-inflammatory herbs have proven beneficial by combating inflammatory responses that lead
to severe abnormality in body systems. Inflammation though a protective response to infection or injury and may result in pathological
outcome when aggravated or of severe degree thus needs an early intervention for proper resolution. Fever is a complex physiologic
response triggered by infectious or aseptic stimuli. Elevations in body temperature occur when concentrations of prostaglandin E (2)
(PGE (2) increase within certain areas of the brain. Carissa carandas L. (Apocynaceae) is a medicinal plant and is widely distributed
in tropical and subtropical regions of India. Meanwhile it is an evergreen shrub that constitutes a continuous source of leaves and stem
throughout the year. The present investigation attempted to find out the anti-inflammatory and anti-pyretic potentials of the methanol
extract of C. carandas L. stem. The extract was evaluated for phytochemical screening, which indicated the presence of steroids,
glycosides, flavonoids, tannins, terpenoids and carbohydrates.