To Determine The Maternal Outcomes In Women Given A Modest Dosage Of Magnesium Sulphate

Abstract

Aim: The aim of this study to determine the maternal outcomes in women given a modest dosage of magnesium sulphate.
Materials and Methods: This research was conducted at the Department of Obstetrics and Gynecology, with clearance from the
institute's ethical committee. Eclampsia patients were placed into two equal groups of 200. Groups 1 (Dhaka regime) and 2 (Pritchard
regime). The trial excluded patients with myasthenia gravis, hepatic coma with danger of renal failure, and magnesium hypersensitivity.
Results: There was no recurrence in 92% of the cases, 3 recurrences in 3% of the cases, and more than 2 recurrences in 3% of the cases.
In group 1, there were only two recurrences in 2% of the cases, and there were none in 98% of the instances. In group 2, there were
one and one recurrence in 1% of the cases, respectively. Maternal problems were noted in 25% of the patients overall. HELLP syndrome
and abruption were recorded in 9% of the cases each, DIC in 5% of the cases, PPH and CVA in 1% of the cases each in group 1, and
total maternal problems in 33% of the cases. Abruption was recorded in 11% of the patients, HELLP syndrome in 8%, and DIC in 6%.
Renal failure and PPH were observed in 3% of the patients, respectively, and CVA in 1% of the cases in Group 2. Maternal mortality
was 3% overall. In 1% of the cases, CVA, DIC, and pulmonary oedema were the causes of death. Overall maternal mortality was 8%
in groups 1 and 2. In 3% of instances, DIC and acute renal failure were the causes of maternal death, whereas pulmonary oedema and
CVA were the causes of mortality in 1% of cases.
Conclusion: There was no statistically significant difference between the groups in the rates of maternal complications or maternal
death. Women in India tend to have a lower body mass index than their Western counterparts, thus a reduced dosage may be ideal for
them. Due to its comparability in efficacy and safety to the Pritchard protocol, this research indicates that low-dose magnesium sulphate
should be used instead.