Utility Of Antioxidants and Nutrients In Sperm Motility And Altered Sperm DNA Fragmentation Levels: A Study Protocol

Authors

  • Aasisjot Kaur
  • Akash More
  • Ujwal Gajbe
  • Deepti Shrivastava

DOI:

https://doi.org/10.47750/pnr.2022.13.03.134

Keywords:

Antioxidants like vitamin-C, vitamin-E , CoenzymQ10 , Zinc , Selenium, Omega- 3 -fatty acids, Reactive oxygen species, Sperm DNA fragmentation levels, Sperm motility.

Abstract

Background: Numerous studies have manifested that sperm deoxyribonucleic acid fragmentation levels can be lowered by use of antioxidants and some studies have shown the consequences of oral antioxidants on sperm chromatin probity. Supplementation of antioxidants in the body is likely to increase the motility and concentration of sperm, and sperm DNA fragmentation. Specific antioxidants such as CoenzymQ10 , Vit-E,C , L-Carnitine are supplemented into the body to decrease oxidative stress, reactive oxygen species further sperm DNA disintegration levels. Supplementation of folate helps in improving the sperm concentration. Further, supplementation of zinc and selenium plays essential role in increasing sperm motility. Objectives: To identify the deficiency of the antioxidants and nutrients in infertile male partner. To study the consequences of antioxidants on motility, morphology and count of sperms. To evaluate sperm DNA disintegration levels before and after performing SCD test. Methodology: This non-invasive methodology includes recording of treatment history and the indications. Counselling of the participants for research will be done. Further protocol include supplementation of antioxidants like CoenzymQ10 , Vit- C, E to study their effects on Sperm kinetics , concentration of sperm and Sperm DNA disintegration levels.

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Published

2022-10-01

Issue

Section

Articles

How to Cite

Utility Of Antioxidants and Nutrients In Sperm Motility And Altered Sperm DNA Fragmentation Levels: A Study Protocol. (2022). Journal of Pharmaceutical Negative Results, 13(3), 901-905. https://doi.org/10.47750/pnr.2022.13.03.134