Evaluating The Diagnostic Accuracy of FNAC of Breast Lesions with Reference To International Academy Of Cytology (IAC) Standardized Reporting And Correlation With Histopathology Of Breast Carcinoma

Authors

  • Dr Priyanka Prakash
  • Dr Eswari V

DOI:

https://doi.org/10.47750/pnr.2022.13.03.124

Keywords:

Breast lesion, Elston's modified Bloom and Richardson method, FNAC, IAC grading, Robinson's grading.

Abstract

Introduction: Breast lesions are the leading cause of morbidity and mortality in women. Fine needle aspiration cytology (FNAC) of
Breast is a significant component of the “Triple approach” for pre-operative diagnosis of breast lumps. This study is undertaken to explore
the utility and accuracy of FNAC in various breast pathologies.
Aim: This study aims to classify various breast lesions according to the International Academy of Cytology (IAC) grading system and
grade breast carcinoma on FNAC using Robinson's grading system which is then correlated with histopathology and also to evaluate the
diagnostic accuracy, sensitivity, and specificity of FNAC in diagnosing breast lesions.
Materials and methods: The study was conducted on patients with breast lump. This study was conducted by retrieving FNAC smears and
were grouped under five standardized categories proposed by the IAC: Category I (Insufficient material), Category II (Benign), Category
III (Atypical), Category IV (Suspicious) & Category V (Malignant) respectively. C5 cases were graded by Robinson's grading system which
was then compared with the histopathological Elston Ellis modified Bloom-Richardson grading system.
Results: Category I, II, III, IV, and V accounted for 10 (12.5%), 43 (53.75%), 3 (3.75%), 5 (6.25%), and 19 (23.75%) of the 80 breast lesions
reported on FNAC, respectively. Histopathology correlations were available in 59 cases. The sensitivity, specificity, positive and negative
predictive value, and diagnostic accuracy were 80%, 100%, 100%, 92.10%, and 94% respectively.
Conclusion: Cytological characterization based on IAC structured reporting will enhance diagnostic clarity and comparison with
histopathology establishes the diagnostic accuracy of FNAC.

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Published

2022-10-02

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Articles

How to Cite

Evaluating The Diagnostic Accuracy of FNAC of Breast Lesions with Reference To International Academy Of Cytology (IAC) Standardized Reporting And Correlation With Histopathology Of Breast Carcinoma. (2022). Journal of Pharmaceutical Negative Results, 13(3), 830-838. https://doi.org/10.47750/pnr.2022.13.03.124