Preformulation Studies Of S-Equol
DOI:
https://doi.org/10.47750/pnr.2022.13.S04.119Keywords:
S-Equol, Preformulation Studies, Molecular weight, Melting point, StabilityAbstract
S-Equol is an intestinal bacterial metabolite of the soybean isoflavone daidzein which has potent Antioxidant, and Anti-inflammatory
properties in humans. Evaluation of solubility, Molecular weight, Melting point, Compatibility, and Stability of the Drug by Preformulation Studies should be determined. Preformulation is the Study of the Physicochemical properties of the drug before the formulation process. This can support the necessity for molecular change or offer crucial information for formulation design. This feature offers the basis for medication combinations with medicinal components in dosage form production. The goal of Preformulation research is to create an elegant, stable, effective, and safe dosage form by creating a kinetic rate profile, compatibility with other components, and establishing physicochemical parameters of novel therapeutic compounds. Among these features, drug solubility, and stability are crucial in Preformulation research. Polymorphism with crystal and amorphous forms of the drug molecule results in different chemical, physical, and therapeutic descriptions. This article describes several qualities and strategies for evaluating medication Preformulation Studies of S-Equol.