Spectrophotometric Determination With Anticancer Drugs, Proton Pump Inhibitors And Antihypertensive Drugs In Non Polar Medium

Abstract

Spectrophotometric methods for the analytical determination of organic, inorganic and biological substances are generally based on development of colour by reagents and identifying such reagents is often cumbersome and time consuming. In this respect, spectrophotometric determination of drugs may be facilitated by their ability to from coloured charge transfer complexes with electron acceptors. In the present investigation, a variety of drugs acting as electron donors e.g. anticancer drugs (Altretamine, Imatinib, Letrozole, Irinotecan) and proton pump inhibitors (Ilaprazole, Omeprazole, Rabeprazole, Lansoprazole, Pantoprazole, Ranitidine) have1been used for spectrophotometric determination in a relatively non polar medium.