Prevention Of Neonatal Adrs- Need For Antimicrobial Stewardship


  • Gannoji Sainath Chary , Md. Sabeeh Uddin , Md. Ilham Ahmed , Raheemunnisa , Dr. Sneha Thakur



Neonatal health is primary public issue attracting huge domestic funds and health policies. Infections that can often increase the neonatal mortality and morbidity are common due to antimicrobial resistance. Antibiotic-resistant infections are posing the primary risk and major challenge of the real time due to the resistance. Numerous cohort studies have demonstrated that continuous exposure and outcomes are associated with significant variations in antibiotic use. We now have a better understanding of how antibiotic-induced variation in antibiotic use and outcomes is caused by studies of antibiotic-induced microbiome alterations and their subsequent effects on the immune system. Even with GBS prophylaxis, premature infants are more likely to develop sepsis than term infants.Antibiotic stewardship is an important ongoing priority; at the same time, antibiotic use will likely remain high among neonates.Gaining knowledge on antimicrobial pharmacokinetics will help in avoiding under-dosing which generally impacts the development of resistant microorganisms.The Global statistics of GARDP(WHO) projected the neonatal sepsis due to antibiotic resistance andproposed antibiotic stewardship.The development of resistant microorganisms can be prevented by developing a better understanding of antimicrobial pharmacokinetics. Antibiotics should be used selectively or with held in neonates through evidence-based antibiotic stewardship programs to reduce the likelihood of any infections and to support clinical approaches that appear to be effective.



2022-12-31 — Updated on 2022-12-31




How to Cite

Prevention Of Neonatal Adrs- Need For Antimicrobial Stewardship. (2022). Journal of Pharmaceutical Negative Results, 4706-4713.