In-Vitro Anti-Lipase And Antioxidant Activities Of Kalanchoe Pinnata Leaves And Ficus Racemosa Fruit Extracts

Abstract

Introduction:  Herbal medicine has a long history of effective use across the world for wide range of medical conditions, and is increasingly seen as a potential area of research and development. This "Divine Plant" Kalanchoe pinnata and Ficus racemosa has a high therapeutic index because of their chemical composition and pharmacological activities.

Methods: We gathered Kalanchoe pinnata leaves and Ficus racemosa fruits from local market and verified by Dr.K.Madhava chetty Assistant professor, Department of Botany S.V University Tirupati. Antioxidant activity of both plant extracts were evaluated using invitro DPPH radical scavenging activity. In addition pancreatic lipase inhibition activity of both plant extracts were also assessed.

Results: Results obtained for FR extract and KP extracts showed that both exhibit considerable DPPH radical scavenging ability on a dose-dependent basis, proving their usefulness as test chemicals. It was found that the DPPH RSA IC50 value was significantly lower for the FR extract than the KP extract, indicating that the FR extract was more effective at scavenging DPPH radicals. In addition, Kalanchoe Pinnata leaves and Ficus racemosa fruits also showed significant pancreatic lipase inhibition. Pancreatic lipase inhibition is more significant with Kalanchoe pinnata when compared to Ficus racemosa.

Conclusion: the present study concludes that hydroalcoholic extracts of Kalanchoe pinnata leaves and Ficus racemosa fruits exhibit significant antioxidant activity as well as pancreatic lipase inhibitory activity. Further research is required to explore and evaluate different pharmacological activities.