Synthesis, Metal Complexing Properties And Antifungal Activity Of Sulpha Drug Containing Ligand
Sulphathiazole (ST), a drug on condensation with tetrahydrophthalic anhydride(THPA) yield a ligand, 6-((4-(N-(thiazol-2-yl) sulfamoyl) phenyl) carbamoyl) cyclohex-3-enecarboxylic acid (THPAST). Metal complexes of THPAST were synthesised with transition metal ions i.e. Cu2+, Co2+, Ni2+, Mn2+, and Zn2+.The synthesised ligands(THPAST) and its metal complexes were analysed by various parameters like elemental analysis, Spectral analysis and magnetic moments. All the samples were monitored against common fungi for their antifungal activity.
2022-12-31 — Updated on 2022-12-31
How to Cite
Chintankumar P. , Piyush V. , Jayesh B. (2022). Synthesis, Metal Complexing Properties And Antifungal Activity Of Sulpha Drug Containing Ligand. Journal of Pharmaceutical Negative Results, 3651–3654. https://doi.org/10.47750/pnr.2022.13.S10.442