Efficacy Of Adjunctive Rtms In Psychogenic Non-Epileptic Seizure In Children And Adolescents: A Randomized Double Blind Sham Controlled Study

Abstract

Transcranial Magnetic Stimulation (TMS) is a non-invasive method of stimulating focal areas of brain, which was initially developed as a tool to study localization of brain, is increasingly been used in neuropsychiatric research and clinical psychiatry. The effects of rTMS depend on the stimulation parameters, such as frequency and intensity (Wassermann et al, 1996). High frequency repetitive transcranial magnetic stimulation (rTMS) induces activation and low frequency rTMS causes inhibition of cerebral cortex, modifying cortical excitability (Pascual-Leone et al, 1998).