Overview Of Proteinuria Among Hospitalized Patients With COVID-19

Abstract

COVID-19 was thought to be primarily a respiratory disease, progressing in some patients to serious respiratory symptoms, pneumonia, severe respiratory distress syndrome and even death.Patients infected with SARS-CoV-2 might have a variety of clinical presentations, ranging from no symptoms to life-threatening sickness. Later analysis revealed entire systems were compromised, affecting other vital organs, including the kidneys, and a correlation was observed between chronic kidney disease (CKD) and COVID-19 severity. A large percentage of affected patients present with acute kidney injury. However, specific phenotypic aspects of acute kidney injury or other renal manifestations of COVID-19 remain sparsely characterized. Urine proteincreatinine ratio (UPCR) in single-voided urine samples correlates well with measurements of 24-hour urinary protein when properly interpreted by taking into consideration the different rates of creatinine excretion. Arguably, knowing the baseline status of proteinuria can be equally important in the assessment of AKI in a hospitalized patient. Many reports indicate that proteinuria can be detected in acute kidney injury associated with COVID-19 despite being largely described as a form of acute tubular injury. Therefore, this study aimed to review acute kidney injury among hospitalized patients with COVID 19.