A Comparative Study Of Intravenous Ondansetron And Placebo For The Reduction Of Spinal Anesthesia

Abstract

Hypotension is among the most regular results of spinal sedation. Since it can change the result of the embryo, maternal hypotension during a cesarean activity is more dangerous. The Bezold Jarisch Reflex (BJR), which brings about bradycardia and hypotension in the circumstance of diminished blood volume, has been shown to be set off by serotonin (5-HT3). A serotonin bad guy called ondansetron might be useful in keeping away from spinal-prompted hypotension. The reason for this study is to perceive how intravenous ondansetron attempts to forestall spinal incited hypotension during cesarean segment. The reason for this study was to perceive what two portions of prophylactic ondansetron meant for spinal sedation actuated hypotension and bradycardia in patients going through elective cesarean births. From Spring to September 2021, this study was led in the obstetric performance centers at Ain Hoaxes Medical clinic. Each eager member gave composed informed assent for the review. Onandsetron 8 mg and, less significantly, 4 mg preventive intravenous boluses could decrease the decrease in parturients' MBP following spinal sedation and how much ephedrine required, which could reduce the gamble of neonatal acidosis welcomed on by ephedrine use.