Anti Aging Activity Of Sambucus Extracts In Vivo And In Vitro Study

Abstract

While many studies have been conducted and published on rosemary essential oil or alcoholic extracts, hexane extracts, which have a very different composition, have received far less attention. Compared to rosemary phenolics extracts prepared with methanol, ethanol, and acetone, rosemary hexane extract has been shown to have superior antioxidant activity and a higher carnosic acid content. To further enhance consumer acceptability, hexane efficiently extracts aroma compounds like monoterpenes, sesquiterpenes, phenylpropenes, and their oxygenated derivatives.  On top of that, hexane is able to extract anti-inflammatory triterpenes, antioxidant tocopherols, and anti-aging and permeation-enhancing saturated and unsaturated fatty acids, whereas polar solvents are unable to do so.  On the other hand, R. ofcinalis hexane extract is seen as a waste product during the agri-food processing of rosemary to create decolorized polyphenol-rich extracts for commercial exploitation as natural antioxidants and antimicrobials in food preservation. This produces substantial amounts of hexane extract waste. To make the process more sustainable and to maximize economic and environmental benefits, it is important to valorize such wastes as sources of phytochemicals needed in various industrial and medicinal applications, thanks to the initiative of circular economy.