Caries Prevention Potential Of Pearl Powder Versus Casein Phosphopeptide-Amorphous Calcium Phosphate On Enamel White Spot Lesions: Randomized Clinical Trial

Abstract

Aim: The current study was conducted to evaluate the caries prevention potential of pearl powder against Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) in enamel white spot lesions.

Methodology: Thirty subjects were randomized into two equal groups (n=15). Group 1 (intervention group) received pearl powder gel, while group 2 (Control group) received Casein Phosphopeptide-Amorphous Calcium Phosphate (GC Tooth-Mousse). The participants were instructed to use pea size amount of pearl powder gel or GC Tooth-Mousse on the teeth surfaces using their finger twice daily after brushing with fluoride-free toothpaste for the first three months, followed by the use of fluoride containing tooth paste for the next 3 month. Quantitative changes of white spot lesions were measured at baseline, three, six, nine, and twelve months using DIAGNOdent pen 2910 (KaVo, Biberach and der Riss, Germany). Data for quantitative changes of white spot lesions were recorded and analysed for each group.

Results: No statistically significant difference was found in overall DIAGNOdent pen mean readings between pearl powder gel and GC Tooth-Mousse groups at P=0.145. On the other hand, the intragroup comparison within both groups showed statistically significant difference between baseline, three, and six months follow-up periods, while after nine and twelve months there was no statistically significant difference among both groups.

Conclusions: Pearl powder gel seem to have a caries prevention efficacy similar to GC Tooth-Mousse and may be considered as promising natural and bioavailable material in reducing the progression of enamel WSLs.