“Preclinical Investigation On The Protective Effect Of Bacopa Monnieri On Human Neuroblastoma Cell Line SH-SY5Y On Its Progressive Development And Finding On Autism Spectrum Disorder”

Authors

  • Dr.P.Muralidharan , Anamika.P.K

DOI:

https://doi.org/10.47750/pnr.2022.13.S09.270

Abstract

Autism is a common neurodevelopmental disorder characterised by differences in societal behaviour and interactive communication, as well as stereotyped, monotonous behaviours, unjustifiably partial to males and females by a ratio of 4:1, and a lack of understanding of the role of sex hormones in autism susceptibility. MTT & SRB Cell Viability Assay Proliferation of Cells Assay The entire study was carried out on differentiated SH-SY5Y cells with varying passage numbers. SH-SY5Y human neuroblastoma cell lines were used in this investigation to expose the circumstances. SH-SY5Y cells seldom produce and distribute neuron-specific proteins at levels equivalent to mature neurons. As a result, differentiated SH-SY5Y cells were used in the majority of neuro research. SH-SY5Y cells were grown and allowed to differentiate for a period of time. Autism spectrum disorder (ASD) is a group of neurodevelopmental diseases marked by a lack of social skills and nonverbal interactions in early childhood, such as decreased eye contact, facial expression, and body motions. SH-SY5Y cell lines were chosen to explore the pattern of ASD. MTT & SRB Cell Viability Assay.

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Published

2022-11-23 — Updated on 2022-11-24

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How to Cite

Dr.P.Muralidharan , Anamika.P.K. (2022). “Preclinical Investigation On The Protective Effect Of Bacopa Monnieri On Human Neuroblastoma Cell Line SH-SY5Y On Its Progressive Development And Finding On Autism Spectrum Disorder”. Journal of Pharmaceutical Negative Results, 2262–2269. https://doi.org/10.47750/pnr.2022.13.S09.270 (Original work published November 23, 2022)

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