Emerging Antibiotic Resistance In Gram-Negatives Isolated From A Tertiary Care Hospital Of Islamabad, Pakistan

Authors

  • Ujala saba , Bibi khadija , Dua , Zahra Rafi ,Muhammad Owais , Farah Shireen , Sobia khan , Hina Gul , Uzma Rubab , Rooh Ullah , Muhammad Jawad Ullah , Rani faryal

DOI:

https://doi.org/10.47750/pnr.2022.13.S09.148

Abstract

Rapidly emerging antibiotic resistance in Gram-negative microorganisms is a serious health issue worldwide. In the present study, antibiotic resistance pattern in 849 isolated Gram-negative bacteria from different clinical sources, over a period of two years (Jan 2017-Dec 2018) was determined in the Microbiology Laboratory of Capital Hospital, Islamabad. Escherichia coli was the prevalent specie isolated from clinical sources followed by Klebsiella pneumonia and Pseudomonas aeruginosa. E. coli isolates also showed a high level of resistance toward third-generation Cephalosporin’s (>50%) and Ciprofloxacin (40% to 51% in two years). K .pneumonia showed enhanced resistance against Ciprofloxacin (38% to 63%) during this period. P. aeruginosa showed increased resistance against second and third-generation Cephalosporin’s (Cefuroxime; 91.9% to 95.4%, Cefixime; 78.4% to 65.4%). Antibiotic resistance among Gram-negative microorganisms is a growing problem, nowadays.Gram-negative microbes isolated in the present study showed high rates of resistance over the period of two years, against commonly prescribed groups of antibiotics in the Pakistani population.

Downloads

Published

2022-11-16 — Updated on 2022-11-16

Versions

How to Cite

Ujala saba , Bibi khadija , Dua , Zahra Rafi ,Muhammad Owais , Farah Shireen , Sobia khan , Hina Gul , Uzma Rubab , Rooh Ullah , Muhammad Jawad Ullah , Rani faryal. (2022). Emerging Antibiotic Resistance In Gram-Negatives Isolated From A Tertiary Care Hospital Of Islamabad, Pakistan. Journal of Pharmaceutical Negative Results, 1257–1264. https://doi.org/10.47750/pnr.2022.13.S09.148

Issue

Section

Articles