Synthesis Of Pyranodiquinoline Derivatives And Their Biological Activity Studies By Using Heterogeneous Magnetic Nano Cobalt Ferrite Catalyst
One-pot cyclization of aromatic aldehyde and 8-hydroxy quinoline in the presence of nano Cobalt ferrite is presented as a flexible method for constructing 7-phenyl-7H-pyrano [3, 2-h: 5, 6-h'] diquinoline derivatives (1a-1e). Under reflux conditions the reaction generates high yields of pyrano diquinoline derivatives. Catalyst, Heterogeneous The FT-IR, XRD, SEM, and TEM were used to characterise the nano Cobalt ferrite particles synthesised via the sol-gel citrate precursor method; the IR, MASS, 1H NMR, and 13C NMR techniques were used to analyse the structures of the synthesised pyrano diquinoline derivatives; and the hole-in-plate bio assay method was used to determine the antibacterial activity. The catalyst was recovered from the reaction mixture using a powerful Neodymium magnet and put back into service in order to produce further pyrano diquinoline derivatives.
- 2022-11-14 (2)
- 2022-11-14 (1)