Comparison Study Of Intrathecal 0.75% Ropivacaine Heavy Versus 0.5% Bupivacaine Heavy For Safety & Efficacy Of Patients Posted For Elective Lower Abdominal Surgeries: A Randomized Comparative Study

Authors

  • PROF.DR.P.S.Shanmugam , Dr. Manikandan Ravi

DOI:

https://doi.org/10.47750/pnr.2022.13.S09.67

Abstract

Introduction: This study was designed to evaluate the safety and efficacy of Intrathecal Ropivacaine and Bupivacaine , who are posted for elective surgery under regional Anesthesia.

Method: After getting approval from the institutional ethical committee and informed consent from patients. 100 patients scheduled for various lower abdominal surgeries. All patients were selected based on ASA 1&2. Patients are randomly selected in two groups (R&B). Group-R  n=50, received 0.75% Ropivacaine heavy Group-B n=50, received 0.5% Bupivacaine heavy.

 Inclusion criteria: Both Gender, ASA 1&2, Age 20-60, Elective lower abdominal surgeries.

Exclusion criteria:  Patient refusal, Emergency surgeries, Local sepsis at site of injection.

Characteristics: In our study, we compared patient with regard to Age, Weight, Height, ASA status, Motor and sensory blockage.

Discussion: The purpose of this study is to evaluate the safety and efficacy of Intrathecal Ropivacaine in comparision with Bupivacaine. We evaluated the Motor and sensory block characteristics. Ropivacaine showed slow onset, slightly faster motor regression than sensory . Total time for sensory regression has been prolonged in Ropivacaine than Bupivacaine in our study.

Conclusion: In our study, the sensory block achieved was maximum with Ropivacaine compared with Bupivacaine. Onset of motor block was rapid in Bupivacaine when  compared to Ropivacaine. This study showed that Ropivacaine has lower level of cephaled  spread of sensory block, but it takes more time for regression of sensory block compared to motor block. Urinary retention  is more with Group-B than Group-R. Hemodynamic stability was better with Ropivacaine compared with  Bupivacaine.

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Published

2022-11-11 — Updated on 2022-11-11

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How to Cite

PROF.DR.P.S.Shanmugam , Dr. Manikandan Ravi. (2022). Comparison Study Of Intrathecal 0.75% Ropivacaine Heavy Versus 0.5% Bupivacaine Heavy For Safety & Efficacy Of Patients Posted For Elective Lower Abdominal Surgeries: A Randomized Comparative Study. Journal of Pharmaceutical Negative Results, 605–611. https://doi.org/10.47750/pnr.2022.13.S09.67

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