Bacteriological Profile of Diabetic Ulcer Foot and Their Antimicrobial Susceptibility Pattern in a Tertiary Care Hospital, Trichy

Authors

  • Prasant HA
  • Lalithambigai J
  • Prabhusaran N

DOI:

https://doi.org/10.47750/pnr.2022.13.S09.010

Keywords:

Diabetic foot ulcer, ESBL, MRSA, Pseudomonas aeruginosa.

Abstract

Background: Wound infections are the major factor for development of diabetic foot ulcer.
Objectives: To identify the prevalence of aerobic bacterial isolates and its antimicrobial susceptibility pattern in diabetic foot ulcer patients.
Methods: The Prospective observational study was undertaken from July 16th to September 16th 2017 in tertiary care teaching Hospital, Tiruchirappalli, Tamilnadu.
Result: Seventy-three (73) organisms were isolated from 63 diabetic foot ulcer patients. Staphylococcus aureus (26%), E. coli (19.2%) and Pseudomonas aeruginosa (19.2%) were isolated. MRSA with 53% were showed 100% sensitivity to vancomycin, linizolid and teicoplanin. By phenotypic Confirmatory Disc Diffusion Test, 57.1% of E. coli were ESBL producers whereas 50% of Klebsiella species were ESBL producers. All ESBL producers showed 100% sensitivity to imipenem.
Interpretation and Conclusion: The microbiological report helps for initiating the narrow spectrum antibiotic therapy and reduce the emergence of multidrug resistant organisms.

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Published

2022-11-07

How to Cite

Prasant HA, Lalithambigai J, & Prabhusaran N. (2022). Bacteriological Profile of Diabetic Ulcer Foot and Their Antimicrobial Susceptibility Pattern in a Tertiary Care Hospital, Trichy. Journal of Pharmaceutical Negative Results, 86–97. https://doi.org/10.47750/pnr.2022.13.S09.010

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Articles