Bacteriological Profile of Diabetic Ulcer Foot and Their Antimicrobial Susceptibility Pattern in a Tertiary Care Hospital, Trichy
Keywords:Diabetic foot ulcer, ESBL, MRSA, Pseudomonas aeruginosa.
Background: Wound infections are the major factor for development of diabetic foot ulcer.
Objectives: To identify the prevalence of aerobic bacterial isolates and its antimicrobial susceptibility pattern in diabetic foot ulcer patients.
Methods: The Prospective observational study was undertaken from July 16th to September 16th 2017 in tertiary care teaching Hospital, Tiruchirappalli, Tamilnadu.
Result: Seventy-three (73) organisms were isolated from 63 diabetic foot ulcer patients. Staphylococcus aureus (26%), E. coli (19.2%) and Pseudomonas aeruginosa (19.2%) were isolated. MRSA with 53% were showed 100% sensitivity to vancomycin, linizolid and teicoplanin. By phenotypic Confirmatory Disc Diffusion Test, 57.1% of E. coli were ESBL producers whereas 50% of Klebsiella species were ESBL producers. All ESBL producers showed 100% sensitivity to imipenem.
Interpretation and Conclusion: The microbiological report helps for initiating the narrow spectrum antibiotic therapy and reduce the emergence of multidrug resistant organisms.